Content area
Abstract
Metastasis is the leading cause of death among patients with solid tumors. Attempts to understand this multi-step biological process at a molecular level are presented in this dissertation, using breast cancer metastasis to the lungs as a prototypic system. Emphasis is placed on clinical validation of metastasis mediators, characterization of the specific functional contribution(s) of molecular mediators to the metastatic cascade, and potential therapeutic implications that these findings may have.
Details
Title
Breast cancer metastasis to the lungs: From genes to mechanisms
Author
Gupta, Gaorav
Year
2007
ISBN
978-0-549-33141-4
Source type
Dissertation or Thesis
Language of publication
English
ProQuest document ID
304742659
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
